Linear 1 3-diarylpropanoids
Medchemexpress LLC Trans-chalcone | 614-47-1 | MFCD00003082 | 98.8% | 208.26 g/mol | C15H12O | 5g
trans-Chalcone isolated from Aronia melanocarpa skin is a biphenolic core structure of flavonoids precursor trans-Chalcone is a potent fatty acid synthase (FAS) and -amylase inhibitor trans-Chalcone causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7 trans-Chalcone has antifungal and anticancer activity[1][2][3]
Medchemexpress LLC PI3K/AKT-IN-1 | 3033069-84-7 | 99.6% | C23H23N5O4S | 10MG
PI3K/AKT-IN-1 is a small-molecule dual inhibitor of the PI3K and AKT signaling pathways, intended for research use in cell signaling and oncology studies. It is supplied as a high-purity solid and is typically prepared in organic solvent for in vitro assays.
- Dual PI3K and AKT pathway inhibition for pathway modulation
- High reported purity suitable for biochemical assays
- Soluble in common organic solvents for assay preparation
- Suitable for cell-based signaling and apoptosis studies
- Characterized molecular data for analytical confirmation
Medchemexpress LLC AKT inhibitor VIII | 612847-09-3 | MFCD23843802 | 99.0% | 551.64 g/mol | C34H29N7O | 100 MG
AKT inhibitor VIII is a cell-permeable, reversible allosteric inhibitor of Akt kinases used as a research reagent to probe PI3K/Akt signaling pathways. It is supplied as a light yellow solid for laboratory use.
- Allosteric, reversible Akt inhibitor.
- Isoform-selective activity with greater potency for Akt1 and Akt2.
- Reported IC50 values: Akt1 = 58 nM, Akt2 = 210 nM.
- Molecular formula C34H29N7O; molecular weight 551.64 g/mol.
- High reported purity (~99%).
- Supplied as a light yellow solid with recommended storage for powder at -20°C or 4°C depending on duration.
TARGETMOL CHEMICALS INC Xanthohumol 10MG
Also available in 1 mL, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-prenylated chalcones. It inhibits COX-1 and COX-2 activity and shows chemopreventive effects. Purity 99.18%
Sigma Aldrich Fine Chemicals Biosciences Phloretin | 60-82-2 | MFCD00002288 | 100mg
Phloretin | 99% | MW: 274.27 | 60-82-2 | MFCD00002288 | 100mg
Medchemexpress LLC Phosphine, diphenyl-1-pyrenyl- | 110231-30-6 | MFCD00278755 | 95.0% | 386.42 | C28H19P | 5 MG
Diphenyl-1-pyrenylphosphine (DPPP) is a fluorogenic peroxide-reactive probe used to detect hydroperoxides and study photophysical behavior. It exhibits phototriggered aggregation-induced emission (AIE) / aggregation-caused quenching (ACQ) transitions and notable third-order nonlinear optical responses. Typically supplied as a solid in small milligram quantities for research use.
- Fluorogenic probe for peroxide and ROS detection.
- Photophysical behavior: AIE/ACQ transitions and third-order nonlinear optical response.
- Purity 95.0%.
- Molecular weight 386.42 Da.
- Chemical formula C28H19P.
- Supplied as a solid powder in milligram quantities.
Selleck Chemical LLC Xanthohumol
Xanthohumol a prenylated chalcone from hop inhibits COX-1 and COX-2 activity and shows chemopreventive effects Xanthohumol inhibits diacylglycerol acyltransferase 1 (DGAT1) and DGAT2 with both IC50 of 40 M Xanthohumol is also a potent antiviral agent against a series of DNA and RNA viruses Xanthohumol induces growth inhibition and apoptosis in cancer cells Phase 1